Neural Information Processing Systems http://nips.cc/

Neural Information Processing Systems http://nips.cc/

A vast swath of modern neuroscience research requires training animals to perform specific tasks.

Accurate predictions of conversion from mild cognitive impairment (MCI) to Alzheimer's disease (AD) can enable effective personalized therapy. While cognitive tests and clinical data are routinely collected, they lack the predictive power of PET scans and CSF biomarker analysis, which are prohibitively expensive to obtain for every patient. To address this cost-accuracy dilemma, we design a two-stage machine learning framework that selectively obtains advanced, costly features based on their predicted "value of information". We apply our framework to predict AD progression for MCI patients using data from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Our framework reduces the need for advanced testing by 20% while achieving a test AUROC of 0.929, comparable to the model that uses both basic and advanced features (AUROC=0.915, p=0.1010). We also provide an example interpretability analysis showing how one may explain the triage decision. Our work presents an interpretable, data-driven framework that optimizes AD diagnostic pathways and balances accuracy with cost, representing a step towards making early, reliable AD prediction more accessible in real-world practice. Future work should consider multiple categories of advanced features and larger-scale validation.

First of all, we would like to thank all the reviewers' valuable comments and their recognition (mainly from R #3 and R We will improve the writing and release the source code. The clustering accuracy dropped from 0.849 to 0.772.

We propose an unsupervised method for detecting loanwords i.e., words borrowed from one language into another. While prior work has primarily relied on language-external information to identify loanwords, such approaches can introduce circularity and constraints into the historical linguistics workflow. In contrast, our model relies solely on language-internal information to process both native and borrowed words in monolingual and multilingual wordlists. By extracting pertinent linguistic features, scoring them, and mapping them probabilistically, we iteratively refine initial results by identifying and generalizing from emerging patterns until convergence. This hybrid approach leverages both linguistic and statistical cues to guide the discovery process. We evaluate our method on the task of isolating loanwords in datasets from six standard Indo-European languages: English, German, French, Italian, Spanish, and Portuguese. Experimental results demonstrate that our model outperforms baseline methods, with strong performance gains observed when scaling to cross-linguistic data.

On the other hand, CG is an indispensable process in which programmers write code to implement specific intents [Balzer, 1985]. Proper comments and correct code can massively improve programmers' productivity and enhance software quality.